理研

次世代ヒト疾患モデル研究開発チーム

次世代ヒト疾患モデル研究開発チーム

english

論文

  • Tada R+, Higashidate T+, Amano T, Ishikawa S, Yokoyama C, Kobari S, Nara S, Ishida K, Kawaguchi A, Ochi H, Ogino H, Yakushiji-Kaminatsui N, Sakamoto J, Kamei Y, Tamura K and Yokoyama A.
    “The shh limb enhancer is activated in patterned limb regeneration but not in hypomorphic limb regeneration in Xenopus laevis”
    Developmental Biology 500, 22-30. (2023).
    (+Authors equally contributed.)
  • Seo H+, Amano T+, Seki R, Sagai T, Kim J, Cho SW and Shiroishi T.
    “Upstream Enhancer Elements of Shh Regulate Oral and Dental Patterning.”
    J. Dent. Res. 97, 1055-1063. (2018).
    (+Authors equally contributed.)
  • Mouri K, Sagai T, Maeno A, Amano T, Toyoda A and Shiroishi T.
    “Enhancer Adoption Caused by Genomic Insertion Elicits Interdigital Shh Expression and Syndactyly in Mouse.”
    Proc. Natl. Acad. Sci. U. S. A. 115, 1021-1026. (2018).
  • Sagai T+, Amano T+, Maeno A, Kiyonari H, Seo H, Cho SW and Shiroishi T.
    “SHH Signaling Directed by Two Oral Epithelium-Specific Enhancers Controls Tooth and Oral Development.”
    Sci. Rep. 7, 13004. (2017).
    (+Authors equally contributed.)
  • Amano T, Sagai T, Seki R and Shiroishi T.
    “Two Types of Etiological Mutation in the Limb-Specific Enhancer of Shh.”
    G3 7, 2991-2998. (2017)
  • Sagai T, Amano T, Maeno A, Kimura T, Nakamoto M, Takehana Y, Naruse K, Okada N, Kiyonari H and Shiroishi T.
    “Evolution of Shh Endoderm Enhancers during Morphological Transition from Ventral Lungs to Dorsal Gas Bladder.”
    Nat. Commun. 3, 8:14300. (2017).
  • Tsukiji N+, Amano T+, and Shiroishi T.
    “A Novel Regulatory Element for Shh Expression in the Lung and Gut of Mouse Embryos.”
    Mech. Dev. 131, 127-136. (2014).
    (+Authors equally contributed.)
  • Tamura M, Hosoya M, Fujita M, Iida T, Amano T, Maeno A, Kataoka T, Otsuka T, Tanaka S, Tomizawa S and Shiroishi T.
    “Overdosage of Hand2 Causes Limb and Heart Defects in the Human Chromosomal Disorder Partial Trisomy Distal 4q.”
    Hum. Mol. Genet. 22, 2471-2481. (2013).
  • Yokoyama H, Maruoka T, Aruga A, Amano T, Ohgo S, Shiroishi T and Tamura K.
    “Prx-1 Expression in Xenopus laevis Scarless Skin-Wound Healing and Its Resemblance to Epimorphic Regeneration.”
    J Invest. Dermatol. 131, 2477-2485. (2011).
  • Sagai T, Amano T, Tamura M, Mizushina Y, Sumiyama K and Shiroishi T.
    “A Cluster of Three Long-Range Enhancers Directs Regional Shh Expression in the Epithelial Linings.”
    Development 136, 1665-1674. (2009).
  • Amano T, Sagai T, Tanabe H, Mizushina Y, Nakazawa H and Shiroishi T.
    “Chromosomal Dynamics at the Shh Locus: Limb Bud-Specific Differential Regulation of Competence and Active Transcription.”
    Dev. Cell 16, 47-57. (2009).

[和文]

  • 天野孝紀
    「遺伝子の発現制御はどこから」、遺伝学用語集 遺伝単、
    株式会社エヌ・ティー・エス、pp104-107、2017
  • 天野孝紀
    「第1章 2節 四倍体胚補完法を利用したCRISPR/Cas9ゲノム改変マウス胚の解析」、『進化するゲノム編集技術』、
    株式会社エヌ・ティー・エス、pp220-225、2015
  • 天野孝紀、城石俊彦
    「シーラカンスの鰭から四肢への進化を考える」生物の科学 遺伝、
    株式会社エヌ・ティー・エス、pp220-225、2014
  • 天野孝紀
    「マウスゲノムを読み解くための新しい文法書」
    生物の科学 遺伝、
    株式会社エヌ・ティー・エス、pp141-144、2013
  • 天野孝紀
    「第I部 生物機能モデルの作製と利用、第1章 発生・形態形成、第5節 中胚葉性器官形成、第4項 四肢」、『生物機能モデルと新しいリソース・リサーチツール』、
    株式会社エル・アイ・シー、pp121-127、2011

Next Generation Human Disease Model Team,

RIKEN BioResource Research Center

3-1-1 Koyadai, Tsukuba, Ibaraki, 305-0074, Japan

Mail: takanori.amano@riken.jp

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