{"id":40,"date":"2018-11-02T16:38:38","date_gmt":"2018-11-02T07:38:38","guid":{"rendered":"http:\/\/hdm.brc.riken.jp\/ja\/?page_id=40"},"modified":"2026-03-31T14:35:18","modified_gmt":"2026-03-31T05:35:18","slug":"publication","status":"publish","type":"page","link":"http:\/\/hdm.brc.riken.jp\/ja\/publication","title":{"rendered":"\u8ad6\u6587"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\">\u8ad6\u6587<\/h2>\n\n\n\n<div id=\"list\">\n\n\n\n<ul class=\"wp-block-list\">\n<li>Yoshida K, Takada T,&nbsp;Muratani&nbsp;M and&nbsp;Amano T<strong>. <\/strong><br><strong>\u201c<strong>Allele-specific gene expression in F1 hybrid mice reveals structural variants affecting macrophage characteristics.<\/strong>\u201d<\/strong><br> <em>Scientific Reports<\/em>, 15, 1, 37846. (2025).&nbsp;<\/li>\n\n\n\n<li>Dinh TTH, Imura C, Shiokawa M, Ayabe S, Yoshiki A, Inoue H and Amano T.<br><strong>\u201cA partial deletion of the Tardbp 3\u00b4UTR affects TDP-43 regulation and leads to motor dysfunction in mice\u201d<\/strong><br><em><em>Experimental Animals<\/em><\/em>&nbsp;75, 1, 25-61. (2025).<\/li>\n\n\n\n<li>Hang A, Shao A, Shea M, Roux MJ,\u202fImai-Leonard DM, Adams DJ,&nbsp;Amano T, Amarie OV,&nbsp;Berberovic&nbsp;Z, Bour R, Bower L, Leonard BC, Brown SD, Cho SY, Clementson-Mobbs S, D&#8217;Souza AJ, Dickinson M, Eskandarian M, Flenniken AM, Fuchs H,&nbsp;Gailus-Durner V, Heaney J,&nbsp;H\u00e9rault&nbsp;Y, Hrabe de Angelis M, Hsu CW, Jin S, Joynson R, Kang YK, Kim H,&nbsp;Masuya&nbsp;H, Nam KH, Noh H, Nutter LMJ,&nbsp;Palkova&nbsp;M, Prochazka J,&nbsp;Raishbrook&nbsp;MJ, Riet F, Salazar J,&nbsp;Seavitt&nbsp;JR, Sedlacek R,&nbsp;Selloum&nbsp;M, Seo KY, Seong JK, Shin HS, Shiroishi T,&nbsp; Sorg T, Stewart M, Tamura M, Tolentino H, Udensi U,&nbsp;Wells&nbsp;S, Wurst W, Yoshiki A, Meziane H, Yiu G, Sieving PA, Lanoue L, Lloyd KCK, McKerlie C and Moshiri A; International Mouse Phenotyping Consortium (IMPC). <br><strong>\u201c<strong>Ocular Phenotyping of Knockout Mice Identifies Genes Associated&nbsp;With&nbsp;Late Adult Retinal Phenotypes.<\/strong>\u201d<\/strong><br><em>Investigative Ophthalmology &amp; Visual Science<\/em>,&nbsp;66, 6,&nbsp;64.&nbsp;(2025).&nbsp;                                                                                                                                                                               <\/li>\n\n\n\n<li>Rahmawati NY, Dinh TTH, Oikawa T,&nbsp;Shinogi&nbsp;A, Ikeda K, Kadota M, Tamura M,&nbsp;Amano T&nbsp;and Yoshiki&nbsp;A. <br><strong><strong>&#8220;Luminescent mouse model of endometriosis: three-dimensional morphology of lesions and cytokine profiles&#8221;<\/strong>  <\/strong><br><em><em>Experimental Animals<\/em><\/em> 74, 4,&nbsp;419-428.&nbsp;(2025).&nbsp;<\/li>\n\n\n\n<li>Briere A, Vo P, Yang B, Adams D,<strong>&nbsp;<\/strong>Amano T,&nbsp;Amarie O,&nbsp;Berberovic&nbsp;Z, Bower L, Brown SDM, Burrill S, Cho SY, Clementson-Mobbs S, D&#8217;souza A, Eskandarian M, Flenniken AM,&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Fuchs H,&nbsp;Gailus-Durner V,&nbsp;H\u00e9rault&nbsp;Y, Hrabe de Angelis M, Jin S, Joynson R, Kang YK,&nbsp;&nbsp;&nbsp;&nbsp;Kim H,&nbsp;Masuya&nbsp;H, Meziane H, Nam KH, Noh H, Nutter LMJ,&nbsp;Palkova&nbsp;M, Prochazka J,&nbsp;Raishbrook&nbsp;MJ, Riet F, Salazar J, Sedlacek R,&nbsp;Selloum&nbsp;M, Seo KY, Seong JK, Shin HS, Shiroishi T, Stewart M, Svenson K, Tamura M, Tolentino H,&nbsp;Wells&nbsp;S, Wurst W, Yoshiki A, Lanoue L, Lloyd KCK, Leonard BC, Roux MJ, McKerlie C and Moshiri A; International Mouse Phenotyping Consortium.<br><strong>\u201c<strong><strong>Systematic Ocular Phenotyping of Knockout Mouse Lines Identifies Genes Associated&nbsp;With&nbsp;Age-Related Corneal Dystrophies<\/strong><\/strong>\u201d<\/strong><br><em>Investigative Ophthalmology &amp; Visual Science<\/em>,&nbsp;66, 5, 7.&nbsp;(2025).&nbsp;&nbsp;                                                                                                                                                                                     <\/li>\n\n\n\n<li>Vo P, Imai-Leonard DM, Yang B, Briere A, Shao A, Casanova MI, Adams D,\u00a0Amano T, Amarie O,\u00a0Berberovic\u00a0Z, Bower L, Braun R, Brown S, Burrill S, Cho SY, Clementson-Mobbs S, D&#8217;Souza A, Dickinson M, Eskandarian M, Flenniken AM, Fuchs H,\u00a0Gailus-Durner V, Heaney J,\u00a0H\u00e9rault\u00a0Y, Angelis MH, Hsu CW, Jin S, Joynson R, Kang YK, Kim H,\u00a0Masuya\u00a0H, Meziane H, Murray S, Nam KH, Noh H, Nutter LMJ,\u00a0Palkova\u00a0M, Prochazka J,\u00a0Raishbrook\u00a0MJ, Riet F, Ryan J, Salazar J, Seavey Z,\u00a0Seavitt\u00a0JR, Sedlacek R,\u00a0Selloum\u00a0M, Seo KY, Seong JK, Shin HS, Shiroishi T, Stewart M, Svenson K, Tamura M, Tolentino H, Udensi U,\u00a0Wells\u00a0S, White J, Willett A, Wotton J, Wurst W, Yoshiki A; International Mouse Phenotyping Consortium; Lanoue L, Lloyd KCK, Leonard BC, Roux MJ, McKerlie C and Moshiri A.<strong> <\/strong><br><strong>\u201c<strong><strong><strong><strong><strong>Systematic ocular phenotyping of 8,707 knockout mouse lines identifies genes associated with abnormal corneal phenotypes<\/strong><\/strong><\/strong><\/strong><\/strong>\u201d<\/strong><br><em><em>EBMC Genomics<\/em><\/em>\u00a026, 1, 48. (2025). <em><em> <\/em><\/em><\/li>\n\n\n\n<li>Hayashi A, Kamio K, Miyanaga A, Yoshida K, Noro R, Matsuda K, Tozuka T,Omori M, Hirao M, Fukuizumi A, Hisakane K, Takeuchi S, Matsumoto M, Kasahara K,<br>Amano T, Honda K and Seike M.<br><strong>\u201cIvermectin Enhances Paclitaxel Efficacy by Overcoming Resistance Through Modulation of&nbsp;ABCB1&nbsp;in Non-small Cell Lung Cancer\u201d<\/strong><br><em>Anticancer Research<\/em>&nbsp;44, (12) 5271-5282. (2024).<\/li>\n\n\n\n<li>Saito A, Tahara R, Hirose M, Kadota M, Hasegawa A, Kondo S, Kato H, Amano T, Yoshiki A, Ogura A and Kiyosawa H.<br><strong>\u201cInter-subspecies mouse F1 hybrid embryonic stem cell lines newly established for studies of allelic imbalance in gene expression\u201d<\/strong><br><em>Experimental Animals<\/em>&nbsp;24-0002. (2024).<\/li>\n\n\n\n<li>Kawashima H, Nishimata S, Shinji S, Morishima Y, Tsutsumi N, Kashiwagi K, Amano T, Tamura M, Ayabe S and Nakashima K.<br><strong>\u201cThree Siblings with Aarskog Scott Syndrome Together with Mental Retardation and Giant Megacolon\u201d<\/strong><br><em>Glob. J. Pedia.<\/em>&nbsp;2, 1, IFN1000278. (2024).<\/li>\n\n\n\n<li>Tada R+, Higashidate T+, Amano T, Ishikawa S, Yokoyama C, Kobari S, Nara S, Ishida K, Kawaguchi A, Ochi H, Ogino H, Yakushiji-Kaminatsui N, Sakamoto J,<br>Kamei Y, Tamura K and Yokoyama A.<br><strong>\u201cThe shh limb enhancer is activated in patterned limb regeneration but not in hypomorphic limb regeneration in Xenopus laevis\u201d<\/strong><br><em>Developmental Biology<\/em>&nbsp;500, 22-30. (2023).<br>(+Authors equally contributed.)<\/li>\n\n\n\n<li>Tanaka S, Orita H, Kataoka T, Miyazaki M, Saeki H, Wada R, Brock MV, Fukunaga T, Amano T, and Shiroishi T.<br><strong>\u201cGasdermin D Represses Inflammation-Induced Colon Cancer Development by Regulating Apoptosis\u201d<\/strong><br><em>Carcinogenesis<\/em>&nbsp;44, 341\u2013349. (2023).<\/li>\n\n\n\n<li>Amano T.<br><strong>\u201cGene regulatory landscape of the sonic hedgehog locus in embryonic development\u201d<\/strong><br><em>Dev. Growth Differ.<\/em>&nbsp;62, 334-342. (2020).<\/li>\n\n\n\n<li>Sagai T, Amano T, Maeno A, Ajima R, and Shiroishi T.<br><strong>\u201cSHH signaling mediated by a prechordal and brain enhancer controls forebrain organization\u201d<\/strong><br><em>Proc. Natl. Acad. Sci. USA<\/em>&nbsp;116, 23636-23642. (2019).<\/li>\n\n\n\n<li>Seo H+, Amano T+, Seki R, Sagai T, Kim J, Cho SW and Shiroishi T.<br><strong>\u201cUpstream Enhancer Elements of Shh Regulate Oral and Dental Patterning.\u201d<\/strong><br><em>J. Dent. Res.<\/em>&nbsp;97, 1055-1063. (2018).<br>(+Authors equally contributed.)<\/li>\n\n\n\n<li>Mouri K, Sagai T, Maeno A, Amano T, Toyoda A and Shiroishi T.<br><strong>\u201cEnhancer Adoption Caused by Genomic Insertion Elicits Interdigital Shh Expression and Syndactyly in Mouse.\u201d<\/strong><br><em>Proc. Natl. Acad. Sci. U. S. A.<\/em>&nbsp;115, 1021-1026. (2018).<\/li>\n\n\n\n<li>Sagai T+, Amano T+, Maeno A, Kiyonari H, Seo H, Cho SW and Shiroishi T.<br><strong>\u201cSHH Signaling Directed by Two Oral Epithelium-Specific Enhancers Controls Tooth and Oral Development.\u201d<\/strong><br><em>Sci. Rep.<\/em>&nbsp;7, 13004. (2017).<br>(+Authors equally contributed.)<\/li>\n\n\n\n<li>Amano T, Sagai T, Seki R and Shiroishi T.<br><strong>\u201cTwo Types of Etiological Mutation in the Limb-Specific Enhancer of Shh.\u201d<\/strong><br><em>G3<\/em>&nbsp;7, 2991-2998. (2017)<\/li>\n\n\n\n<li>Sagai T, Amano T, Maeno A, Kimura T, Nakamoto M, Takehana Y, Naruse K, Okada N, Kiyonari H and Shiroishi T.<br><strong>\u201cEvolution of Shh Endoderm Enhancers during Morphological Transition from Ventral Lungs to Dorsal Gas Bladder.\u201d<\/strong><br><em>Nat. Commun.<\/em>&nbsp;3, 8:14300. (2017).<\/li>\n\n\n\n<li>Tsukiji N+, Amano T+, and Shiroishi T.<br><strong>\u201cA Novel Regulatory Element for Shh Expression in the Lung and Gut of Mouse Embryos.\u201d<\/strong><br><em>Mech. Dev.<\/em>&nbsp;131, 127-136. (2014).<br>(+Authors equally contributed.)<\/li>\n\n\n\n<li>Tamura M, Hosoya M, Fujita M, Iida T, Amano T, Maeno A, Kataoka T, Otsuka T, Tanaka S, Tomizawa S and Shiroishi T.<br><strong>\u201cOverdosage of Hand2 Causes Limb and Heart Defects in the Human Chromosomal Disorder Partial Trisomy Distal 4q.\u201d<\/strong><br><em>Hum. Mol. Genet.<\/em>&nbsp;22, 2471-2481. (2013).<\/li>\n\n\n\n<li>Yokoyama H, Maruoka T, Aruga A, Amano T, Ohgo S, Shiroishi T and Tamura K.<br><strong>\u201cPrx-1 Expression in Xenopus laevis Scarless Skin-Wound Healing and Its Resemblance to Epimorphic Regeneration.\u201d<\/strong><br><em>J Invest. Dermatol.<\/em>&nbsp;131, 2477-2485. (2011).<\/li>\n\n\n\n<li>Sagai T, Amano T, Tamura M, Mizushina Y, Sumiyama K and Shiroishi T.<br><strong>\u201cA Cluster of Three Long-Range Enhancers Directs Regional Shh Expression in the Epithelial Linings.\u201d<\/strong><br><em>Development<\/em>&nbsp;136, 1665-1674. (2009).<\/li>\n\n\n\n<li>Amano T, Sagai T, Tanabe H, Mizushina Y, Nakazawa H and Shiroishi T.<br><strong>\u201cChromosomal Dynamics at the Shh Locus: Limb Bud-Specific Differential Regulation of Competence and Active Transcription.\u201d<\/strong><br><em>Dev. Cell<\/em>&nbsp;16, 47-57. (2009).<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\">[\u548c\u6587]<\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u5929\u91ce\u5b5d\u7d00<br><strong>\u300c\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u5236\u5fa1\u306f\u3069\u3053\u304b\u3089\u300d\u3001\u907a\u4f1d\u5b66\u7528\u8a9e\u96c6\u3000\u907a\u4f1d\u5358\u3001<\/strong><br>\u682a\u5f0f\u4f1a\u793e\u30a8\u30cc\u30fb\u30c6\u30a3\u30fc\u30fb\u30a8\u30b9\u3001pp104-107\u30012017<\/li>\n\n\n\n<li>\u5929\u91ce\u5b5d\u7d00<br><strong>\u300c\u7b2c1\u7ae0\u30002\u7bc0\u3000\u56db\u500d\u4f53\u80da\u88dc\u5b8c\u6cd5\u3092\u5229\u7528\u3057\u305fCRISPR\/Cas9\u30b2\u30ce\u30e0\u6539\u5909\u30de\u30a6\u30b9\u80da\u306e\u89e3\u6790\u300d\u3001\u300e\u9032\u5316\u3059\u308b\u30b2\u30ce\u30e0\u7de8\u96c6\u6280\u8853\u300f\u3001<\/strong><br>\u682a\u5f0f\u4f1a\u793e\u30a8\u30cc\u30fb\u30c6\u30a3\u30fc\u30fb\u30a8\u30b9\u3001pp220-225\u30012015<\/li>\n\n\n\n<li>\u5929\u91ce\u5b5d\u7d00\u3001\u57ce\u77f3\u4fca\u5f66<br><strong>\u300c\u30b7\u30fc\u30e9\u30ab\u30f3\u30b9\u306e\u9c2d\u304b\u3089\u56db\u80a2\u3078\u306e\u9032\u5316\u3092\u8003\u3048\u308b\u300d\u751f\u7269\u306e\u79d1\u5b66 \u907a\u4f1d\u3001<\/strong><br>\u682a\u5f0f\u4f1a\u793e\u30a8\u30cc\u30fb\u30c6\u30a3\u30fc\u30fb\u30a8\u30b9\u3001pp220-225\u30012014<\/li>\n\n\n\n<li>\u5929\u91ce\u5b5d\u7d00<br><strong>\u300c\u30de\u30a6\u30b9\u30b2\u30ce\u30e0\u3092\u8aad\u307f\u89e3\u304f\u305f\u3081\u306e\u65b0\u3057\u3044\u6587\u6cd5\u66f8\u300d<\/strong><br>\u751f\u7269\u306e\u79d1\u5b66 \u907a\u4f1d\u3001<br>\u682a\u5f0f\u4f1a\u793e\u30a8\u30cc\u30fb\u30c6\u30a3\u30fc\u30fb\u30a8\u30b9\u3001pp141-144\u30012013<\/li>\n\n\n\n<li>\u5929\u91ce\u5b5d\u7d00<br><strong>\u300c\u7b2cI\u90e8 \u751f\u7269\u6a5f\u80fd\u30e2\u30c7\u30eb\u306e\u4f5c\u88fd\u3068\u5229\u7528\u3001\u7b2c1\u7ae0 \u767a\u751f\u30fb\u5f62\u614b\u5f62\u6210\u3001\u7b2c5\u7bc0 \u4e2d\u80da\u8449\u6027\u5668\u5b98\u5f62\u6210\u3001\u7b2c4\u9805 \u56db\u80a2\u300d\u3001\u300e\u751f\u7269\u6a5f\u80fd\u30e2\u30c7\u30eb\u3068\u65b0\u3057\u3044\u30ea\u30bd\u30fc\u30b9\u30fb\u30ea\u30b5\u30fc\u30c1\u30c4\u30fc\u30eb\u300f\u3001<\/strong><br>\u682a\u5f0f\u4f1a\u793e\u30a8\u30eb\u30fb\u30a2\u30a4\u30fb\u30b7\u30fc\u3001pp121-127\u30012011<\/li>\n<\/ul>\n\n\n\n<\/div>\n\n\n","protected":false},"excerpt":{"rendered":"<p>\u8ad6\u6587 [\u548c\u6587]<\/p>\n","protected":false},"author":8,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_seopress_robots_primary_cat":"","_seopress_titles_title":"","_seopress_titles_desc":"","_seopress_robots_index":"","footnotes":"","_wp_rev_ctl_limit":""},"class_list":["post-40","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"http:\/\/hdm.brc.riken.jp\/ja\/wp-json\/wp\/v2\/pages\/40","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/hdm.brc.riken.jp\/ja\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/hdm.brc.riken.jp\/ja\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/hdm.brc.riken.jp\/ja\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"http:\/\/hdm.brc.riken.jp\/ja\/wp-json\/wp\/v2\/comments?post=40"}],"version-history":[{"count":9,"href":"http:\/\/hdm.brc.riken.jp\/ja\/wp-json\/wp\/v2\/pages\/40\/revisions"}],"predecessor-version":[{"id":669,"href":"http:\/\/hdm.brc.riken.jp\/ja\/wp-json\/wp\/v2\/pages\/40\/revisions\/669"}],"wp:attachment":[{"href":"http:\/\/hdm.brc.riken.jp\/ja\/wp-json\/wp\/v2\/media?parent=40"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}