{"id":25,"date":"2018-11-09T10:56:36","date_gmt":"2018-11-09T01:56:36","guid":{"rendered":"http:\/\/hdm.brc.riken.jp\/en\/?page_id=25"},"modified":"2026-09-08T08:50:34","modified_gmt":"2026-09-07T23:50:34","slug":"publication","status":"publish","type":"page","link":"http:\/\/hdm.brc.riken.jp\/en\/publication","title":{"rendered":"Publication"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\">Publication<\/h2>\n\n\n\n<div id=\"list\">\n\n\n\n<ul class=\"wp-block-list\">\n<li>Yoshida K, Takada T,&nbsp;Muratani&nbsp;M and&nbsp;Amano T<strong>. <\/strong><br><strong>\u201c<strong>Allele-specific gene expression in F1 hybrid mice reveals structural variants affecting macrophage characteristics.<\/strong>\u201d<\/strong><br> <em>Scientific Reports<\/em>, 15, 1, 37846. (2025).&nbsp;<\/li>\n\n\n\n<li>Dinh TTH, Imura C, Shiokawa M, Ayabe S, Yoshiki A, Inoue H and Amano T.<br><strong>\u201cA partial deletion of the Tardbp 3\u00b4UTR affects TDP-43 regulation and leads to motor dysfunction in mice\u201d<\/strong><br><em><em>Experimental Animals<\/em><\/em>&nbsp;75, 1, 25-61. (2025).<\/li>\n\n\n\n<li>Hang A, Shao A, Shea M, Roux MJ,\u202fImai-Leonard DM, Adams DJ,&nbsp;Amano T, Amarie OV,&nbsp;Berberovic&nbsp;Z, Bour R, Bower L, Leonard BC, Brown SD, Cho SY, Clementson-Mobbs S, D&#8217;Souza AJ, Dickinson M, Eskandarian M, Flenniken AM, Fuchs H,&nbsp;Gailus-Durner V, Heaney J,&nbsp;H\u00e9rault&nbsp;Y, Hrabe de Angelis M, Hsu CW, Jin S, Joynson R, Kang YK, Kim H,&nbsp;Masuya&nbsp;H, Nam KH, Noh H, Nutter LMJ,&nbsp;Palkova&nbsp;M, Prochazka J,&nbsp;Raishbrook&nbsp;MJ, Riet F, Salazar J,&nbsp;Seavitt&nbsp;JR, Sedlacek R,&nbsp;Selloum&nbsp;M, Seo KY, Seong JK, Shin HS, Shiroishi T,&nbsp; Sorg T, Stewart M, Tamura M, Tolentino H, Udensi U,&nbsp;Wells&nbsp;S, Wurst W, Yoshiki A, Meziane H, Yiu G, Sieving PA, Lanoue L, Lloyd KCK, McKerlie C and Moshiri A; International Mouse Phenotyping Consortium (IMPC). <br><strong>\u201c<strong>Ocular Phenotyping of Knockout Mice Identifies Genes Associated&nbsp;With&nbsp;Late Adult Retinal Phenotypes.<\/strong>\u201d<\/strong><br><em>Investigative Ophthalmology &amp; Visual Science<\/em>,&nbsp;66, 6,&nbsp;64.&nbsp;(2025).&nbsp;                                                                                                                                                                               <\/li>\n\n\n\n<li>Rahmawati NY, Dinh TTH, Oikawa T,&nbsp;Shinogi&nbsp;A, Ikeda K, Kadota M, Tamura M,&nbsp;Amano T&nbsp;and Yoshiki&nbsp;A. <br><strong><strong>&#8220;Luminescent mouse model of endometriosis: three-dimensional morphology of lesions and cytokine profiles&#8221;<\/strong>  <\/strong><br><em><em>Experimental Animals<\/em><\/em> 74, 4,&nbsp;419-428.&nbsp;(2025).&nbsp;<\/li>\n\n\n\n<li>Briere A, Vo P, Yang B, Adams D,<strong>&nbsp;<\/strong>Amano T,&nbsp;Amarie O,&nbsp;Berberovic&nbsp;Z, Bower L, Brown SDM, Burrill S, Cho SY, Clementson-Mobbs S, D&#8217;souza A, Eskandarian M, Flenniken AM,&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Fuchs H,&nbsp;Gailus-Durner V,&nbsp;H\u00e9rault&nbsp;Y, Hrabe de Angelis M, Jin S, Joynson R, Kang YK,&nbsp;&nbsp;&nbsp;&nbsp;Kim H,&nbsp;Masuya&nbsp;H, Meziane H, Nam KH, Noh H, Nutter LMJ,&nbsp;Palkova&nbsp;M, Prochazka J,&nbsp;Raishbrook&nbsp;MJ, Riet F, Salazar J, Sedlacek R,&nbsp;Selloum&nbsp;M, Seo KY, Seong JK, Shin HS, Shiroishi T, Stewart M, Svenson K, Tamura M, Tolentino H,&nbsp;Wells&nbsp;S, Wurst W, Yoshiki A, Lanoue L, Lloyd KCK, Leonard BC, Roux MJ, McKerlie C and Moshiri A; International Mouse Phenotyping Consortium.<br><strong>\u201c<strong><strong>Systematic Ocular Phenotyping of Knockout Mouse Lines Identifies Genes Associated&nbsp;With&nbsp;Age-Related Corneal Dystrophies<\/strong><\/strong>\u201d<\/strong><br><em>Investigative Ophthalmology &amp; Visual Science<\/em>,&nbsp;66, 5, 7.&nbsp;(2025).&nbsp;&nbsp;                                                                                                                                                                                     <\/li>\n\n\n\n<li>Vo P, Imai-Leonard DM, Yang B, Briere A, Shao A, Casanova MI, Adams D,&nbsp;Amano T, Amarie O,&nbsp;Berberovic&nbsp;Z, Bower L, Braun R, Brown S, Burrill S, Cho SY, Clementson-Mobbs S, D&#8217;Souza A, Dickinson M, Eskandarian M, Flenniken AM, Fuchs H,&nbsp;Gailus-Durner V, Heaney J,&nbsp;H\u00e9rault&nbsp;Y, Angelis MH, Hsu CW, Jin S, Joynson R, Kang YK, Kim H,&nbsp;Masuya&nbsp;H, Meziane H, Murray S, Nam KH, Noh H, Nutter LMJ,&nbsp;Palkova&nbsp;M, Prochazka J,&nbsp;Raishbrook&nbsp;MJ, Riet F, Ryan J, Salazar J, Seavey Z,&nbsp;Seavitt&nbsp;JR, Sedlacek R,&nbsp;Selloum&nbsp;M, Seo KY, Seong JK, Shin HS, Shiroishi T, Stewart M, Svenson K, Tamura M, Tolentino H, Udensi U,&nbsp;Wells&nbsp;S, White J, Willett A, Wotton J, Wurst W, Yoshiki A; International Mouse Phenotyping Consortium; Lanoue L, Lloyd KCK, Leonard BC, Roux MJ, McKerlie C and Moshiri A.<strong> <\/strong><br><strong>\u201c<strong><strong><strong><strong><strong>Systematic ocular phenotyping of 8,707 knockout mouse lines identifies genes associated with abnormal corneal phenotypes<\/strong><\/strong><\/strong><\/strong><\/strong>\u201d<\/strong><br><em><em>EBMC Genomics<\/em><\/em>&nbsp;26, 1, 48. (2025). <em><em> <\/em><\/em><\/li>\n\n\n\n<li>Hayashi A, Kamio K, Miyanaga A, Yoshida K, Noro R, Matsuda K, Tozuka T,Omori M, Hirao M, Fukuizumi A, Hisakane K, Takeuchi S, Matsumoto M, Kasahara K,<br>Amano T, Honda K and Seike M.<br><strong>\u201cIvermectin Enhances Paclitaxel Efficacy by Overcoming Resistance Through Modulation of&nbsp;ABCB1&nbsp;in Non-small Cell Lung Cancer\u201d<\/strong><br><em>Anticancer Research<\/em>&nbsp;44, (12) 5271-5282. (2024).<\/li>\n\n\n\n<li>Saito A, Tahara R, Hirose M, Kadota M, Hasegawa A, Kondo S, Kato H, Amano T, Yoshiki A, Ogura A and Kiyosawa H.<br><strong>\u201cInter-subspecies mouse F1 hybrid embryonic stem cell lines newly established for studies of allelic imbalance in gene expression\u201d<\/strong><br><em>Experimental Animals<\/em>&nbsp;24-0002. (2024).<\/li>\n\n\n\n<li>Kawashima H, Nishimata S, Shinji S, Morishima Y, Tsutsumi N, Kashiwagi K, Amano T, Tamura M, Ayabe S and Nakashima K.<br><strong>\u201cThree Siblings with Aarskog Scott Syndrome Together with Mental Retardation and Giant Megacolon\u201d<\/strong><br><em>Glob. J. Pedia.<\/em>&nbsp;2, 1, IFN1000278. (2024).<\/li>\n\n\n\n<li>Tada R+, Higashidate T+, Amano T, Ishikawa S, Yokoyama C, Kobari S, Nara S, Ishida K, Kawaguchi A, Ochi H, Ogino H, Yakushiji-Kaminatsui N, Sakamoto J,<br>Kamei Y, Tamura K and Yokoyama H.<br><strong>\u201cThe shh limb enhancer is activated in patterned limb regeneration but not in hypomorphic limb regeneration in Xenopus laevis\u201d<\/strong><br><em>Developmental Biology<\/em>\u00a0500, 22-30. (2023).<br>(+Authors equally contributed.)<\/li>\n\n\n\n<li>Tanaka S, Orita H, Kataoka T, Miyazaki M, Saeki H, Wada R, Brock MV, Fukunaga T, Amano T, and Shiroishi T.<br><strong>\u201cGasdermin D Represses Inflammation-Induced Colon Cancer Development by Regulating Apoptosis\u201d<\/strong><br><em>Carcinogenesis<\/em>&nbsp;44, 341\u2013349. (2023).<\/li>\n\n\n\n<li>Amano T.<br><strong>\u201cGene regulatory landscape of the sonic hedgehog locus in embryonic development\u201d<\/strong><br><em>Dev. Growth Differ.<\/em>&nbsp;62, 334-342. (2020).<\/li>\n\n\n\n<li>Sagai T, Amano T, Maeno A, Ajima R, and Shiroishi T.<br><strong>\u201cSHH signaling mediated by a prechordal and brain enhancer controls forebrain organization\u201d<\/strong><br><em>Proc. Natl. Acad. Sci. USA<\/em>&nbsp;116, 23636-23642. (2019).<\/li>\n\n\n\n<li>Seo H+, Amano T+, Seki R, Sagai T, Kim J, Cho SW and Shiroishi T.<br><strong>\u201cUpstream Enhancer Elements of Shh Regulate Oral and Dental Patterning.\u201d<\/strong><br><em>J. Dent. Res.<\/em>&nbsp;97, 1055-1063. (2018).<br>(+Authors equally contributed.)<\/li>\n\n\n\n<li>Mouri K, Sagai T, Maeno A, Amano T, Toyoda A and Shiroishi T.<br><strong>\u201cEnhancer Adoption Caused by Genomic Insertion Elicits Interdigital Shh Expression and Syndactyly in Mouse.\u201d<\/strong><br><em>Proc. Natl. Acad. Sci. U. S. A.<\/em>&nbsp;115, 1021-1026. (2018).<\/li>\n\n\n\n<li>Sagai T+, Amano T+, Maeno A, Kiyonari H, Seo H, Cho SW and Shiroishi T.<br><strong>\u201cSHH Signaling Directed by Two Oral Epithelium-Specific Enhancers Controls Tooth and Oral Development.\u201d<\/strong><br><em>Sci. Rep.<\/em>&nbsp;7, 13004. (2017).<br>(+Authors equally contributed.)<\/li>\n\n\n\n<li>Amano T, Sagai T, Seki R and Shiroishi T.<br><strong>\u201cTwo Types of Etiological Mutation in the Limb-Specific Enhancer of Shh.\u201d<\/strong><br><em>G3<\/em>&nbsp;7, 2991-2998. (2017)<\/li>\n\n\n\n<li>Sagai T, Amano T, Maeno A, Kimura T, Nakamoto M, Takehana Y, Naruse K, Okada N, Kiyonari H and Shiroishi T.<br><strong>\u201cEvolution of Shh Endoderm Enhancers during Morphological Transition from Ventral Lungs to Dorsal Gas Bladder.\u201d<\/strong><br><em>Nat. Commun.<\/em>&nbsp;3, 8:14300. (2017).<\/li>\n\n\n\n<li>Tsukiji N+, Amano T+, and Shiroishi T.<br><strong>\u201cA Novel Regulatory Element for Shh Expression in the Lung and Gut of Mouse Embryos.\u201d<\/strong><br><em>Mech. Dev.<\/em>&nbsp;131, 127-136. (2014).<br>(+Authors equally contributed.)<\/li>\n\n\n\n<li>Tamura M, Hosoya M, Fujita M, Iida T, Amano T, Maeno A, Kataoka T, Otsuka T, Tanaka S, Tomizawa S and Shiroishi T.<br><strong>\u201cOverdosage of Hand2 Causes Limb and Heart Defects in the Human Chromosomal Disorder Partial Trisomy Distal 4q.\u201d<\/strong><br><em>Hum. Mol. Genet.<\/em>&nbsp;22, 2471-2481. (2013).<\/li>\n\n\n\n<li>Yokoyama H, Maruoka T, Aruga A, Amano T, Ohgo S, Shiroishi T and Tamura K.<br><strong>\u201cPrx-1 Expression in Xenopus laevis Scarless Skin-Wound Healing and Its Resemblance to Epimorphic Regeneration.\u201d<\/strong><br><em>J Invest. Dermatol.<\/em>&nbsp;131, 2477-2485. (2011).<\/li>\n\n\n\n<li>Sagai T, Amano T, Tamura M, Mizushina Y, Sumiyama K and Shiroishi T.<br><strong>\u201cA Cluster of Three Long-Range Enhancers Directs Regional Shh Expression in the Epithelial Linings.\u201d<\/strong><br><em>Development<\/em>&nbsp;136, 1665-1674. (2009).<\/li>\n\n\n\n<li>Amano T, Sagai T, Tanabe H, Mizushina Y, Nakazawa H and Shiroishi T.<br><strong>\u201cChromosomal Dynamics at the Shh Locus: Limb Bud-Specific Differential Regulation of Competence and Active Transcription.\u201d<\/strong><br><em>Dev. Cell<\/em>&nbsp;16, 47-57. (2009).<\/li>\n<\/ul>\n\n\n\n<h4 class=\"wp-block-heading\">[\u548c\u6587]<\/h4>\n\n\n\n<ul class=\"wp-block-list\">\n<li>\u5929\u91ce\u5b5d\u7d00<br><strong>\u300c\u907a\u4f1d\u5b50\u306e\u767a\u73fe\u5236\u5fa1\u306f\u3069\u3053\u304b\u3089\u300d\u3001\u907a\u4f1d\u5b66\u7528\u8a9e\u96c6\u3000\u907a\u4f1d\u5358\u3001<\/strong><br>\u682a\u5f0f\u4f1a\u793e\u30a8\u30cc\u30fb\u30c6\u30a3\u30fc\u30fb\u30a8\u30b9\u3001pp104-107\u30012017<\/li>\n\n\n\n<li>\u5929\u91ce\u5b5d\u7d00<br><strong>\u300c\u7b2c1\u7ae0\u30002\u7bc0\u3000\u56db\u500d\u4f53\u80da\u88dc\u5b8c\u6cd5\u3092\u5229\u7528\u3057\u305fCRISPR\/Cas9\u30b2\u30ce\u30e0\u6539\u5909\u30de\u30a6\u30b9\u80da\u306e\u89e3\u6790\u300d\u3001\u300e\u9032\u5316\u3059\u308b\u30b2\u30ce\u30e0\u7de8\u96c6\u6280\u8853\u300f\u3001<\/strong><br>\u682a\u5f0f\u4f1a\u793e\u30a8\u30cc\u30fb\u30c6\u30a3\u30fc\u30fb\u30a8\u30b9\u3001pp220-225\u30012015<\/li>\n\n\n\n<li>\u5929\u91ce\u5b5d\u7d00\u3001\u57ce\u77f3\u4fca\u5f66<br><strong>\u300c\u30b7\u30fc\u30e9\u30ab\u30f3\u30b9\u306e\u9c2d\u304b\u3089\u56db\u80a2\u3078\u306e\u9032\u5316\u3092\u8003\u3048\u308b\u300d\u751f\u7269\u306e\u79d1\u5b66 \u907a\u4f1d\u3001<\/strong><br>\u682a\u5f0f\u4f1a\u793e\u30a8\u30cc\u30fb\u30c6\u30a3\u30fc\u30fb\u30a8\u30b9\u3001pp220-225\u30012014<\/li>\n\n\n\n<li>\u5929\u91ce\u5b5d\u7d00<br><strong>\u300c\u30de\u30a6\u30b9\u30b2\u30ce\u30e0\u3092\u8aad\u307f\u89e3\u304f\u305f\u3081\u306e\u65b0\u3057\u3044\u6587\u6cd5\u66f8\u300d<\/strong><br>\u751f\u7269\u306e\u79d1\u5b66 \u907a\u4f1d\u3001<br>\u682a\u5f0f\u4f1a\u793e\u30a8\u30cc\u30fb\u30c6\u30a3\u30fc\u30fb\u30a8\u30b9\u3001pp141-144\u30012013<\/li>\n\n\n\n<li>\u5929\u91ce\u5b5d\u7d00<br><strong>\u300c\u7b2cI\u90e8 \u751f\u7269\u6a5f\u80fd\u30e2\u30c7\u30eb\u306e\u4f5c\u88fd\u3068\u5229\u7528\u3001\u7b2c1\u7ae0 \u767a\u751f\u30fb\u5f62\u614b\u5f62\u6210\u3001\u7b2c5\u7bc0 \u4e2d\u80da\u8449\u6027\u5668\u5b98\u5f62\u6210\u3001\u7b2c4\u9805 \u56db\u80a2\u300d\u3001\u300e\u751f\u7269\u6a5f\u80fd\u30e2\u30c7\u30eb\u3068\u65b0\u3057\u3044\u30ea\u30bd\u30fc\u30b9\u30fb\u30ea\u30b5\u30fc\u30c1\u30c4\u30fc\u30eb\u300f\u3001<\/strong><br>\u682a\u5f0f\u4f1a\u793e\u30a8\u30eb\u30fb\u30a2\u30a4\u30fb\u30b7\u30fc\u3001pp121-127\u30012011<\/li>\n\n\n\n<li><\/li>\n<\/ul>\n\n\n\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Publication [\u548c\u6587]<\/p>\n","protected":false},"author":8,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_seopress_titles_title":"","_seopress_titles_desc":"","_seopress_robots_index":"","_seopress_robots_follow":"","_seopress_robots_imageindex":"","_seopress_robots_snippet":"","_seopress_robots_primary_cat":"","_seopress_robots_breadcrumbs":"","_seopress_robots_freeze_modified_date":"","_seopress_robots_custom_modified_date":"","_seopress_robots_canonical":"","_seopress_social_fb_title":"","_seopress_social_fb_desc":"","_seopress_social_fb_img":"","_seopress_social_fb_img_attachment_id":0,"_seopress_social_fb_img_width":0,"_seopress_social_fb_img_height":0,"_seopress_social_twitter_title":"","_seopress_social_twitter_desc":"","_seopress_social_twitter_img":"","_seopress_social_twitter_img_attachment_id":0,"_seopress_social_twitter_img_width":0,"_seopress_social_twitter_img_height":0,"_seopress_redirections_value":"","_seopress_redirections_enabled":"","_seopress_redirections_enabled_regex":"","_seopress_redirections_logged_status":"both","_seopress_redirections_param":"","_seopress_redirections_type":301,"_seopress_analysis_target_kw":"","footnotes":"","_wp_rev_ctl_limit":""},"class_list":["post-25","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"http:\/\/hdm.brc.riken.jp\/en\/wp-json\/wp\/v2\/pages\/25","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/hdm.brc.riken.jp\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/hdm.brc.riken.jp\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/hdm.brc.riken.jp\/en\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"http:\/\/hdm.brc.riken.jp\/en\/wp-json\/wp\/v2\/comments?post=25"}],"version-history":[{"count":11,"href":"http:\/\/hdm.brc.riken.jp\/en\/wp-json\/wp\/v2\/pages\/25\/revisions"}],"predecessor-version":[{"id":736,"href":"http:\/\/hdm.brc.riken.jp\/en\/wp-json\/wp\/v2\/pages\/25\/revisions\/736"}],"wp:attachment":[{"href":"http:\/\/hdm.brc.riken.jp\/en\/wp-json\/wp\/v2\/media?parent=25"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}