{"id":22,"date":"2018-11-09T10:47:24","date_gmt":"2018-11-09T01:47:24","guid":{"rendered":"http:\/\/hdm.brc.riken.jp\/en\/?page_id=22"},"modified":"2025-08-22T16:05:29","modified_gmt":"2025-08-22T07:05:29","slug":"top-page","status":"publish","type":"page","link":"http:\/\/hdm.brc.riken.jp\/en\/","title":{"rendered":"Top page"},"content":{"rendered":"\n<h2 class=\"wp-block-heading\">Research Summary<\/h2>\n\n\n\n<p>Starting from patient genomic data, we introduce disease-associated variants into mice and analyze the resulting pathological phenotypes. The knowledge gained supports the development of diagnostics and therapies, feeding back into clinical practice. Our mission is to bridge the gap between basic research and clinical medicine, contributing to the future of healthcare.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter\"><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"500\" src=\"\/en\/wp-content\/uploads\/fig1-en.png\" alt=\"fig1-en\" class=\"wp-image-35\"\/><\/figure>\n<\/div>\n\n\n<div class=\"wp-block-snow-monkey-blocks-container smb-container c-container smb-container--no-gutters\"><div class=\"smb-container__body is-layout-constrained wp-block-snow-monkey-blocks-container-is-layout-constrained\" style=\"width:800px\">\n<h4 class=\"wp-block-heading\">\u30fbGeneration of genome-edited mice based on patient-derived genomic variants, <br>in collaboration with the Experimental Animal Division.<\/h4>\n\n\n\n<h4 class=\"wp-block-heading\">\u30fbPathological Phenotyping through internationally standard platforms,<br> in collaboration with the Mouse Phenomics Division.<\/h4>\n\n\n\n<h4 class=\"wp-block-heading\">\u30fbInvestigation of disease mechanisms and preclinical drug discovery, <br>in collaboration with external clinical researchers.<\/h4>\n<\/div><\/div>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Research Summary Starting from patient genomic data, we introduce disease-associ &#8230; <\/p>\n","protected":false},"author":8,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"front-page.php","meta":{"_acf_changed":false,"_seopress_robots_primary_cat":"","_seopress_titles_title":"","_seopress_titles_desc":"","_seopress_robots_index":"","_seopress_analysis_target_kw":"","footnotes":"","_wp_rev_ctl_limit":""},"class_list":["post-22","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"http:\/\/hdm.brc.riken.jp\/en\/wp-json\/wp\/v2\/pages\/22","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/hdm.brc.riken.jp\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/hdm.brc.riken.jp\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/hdm.brc.riken.jp\/en\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"http:\/\/hdm.brc.riken.jp\/en\/wp-json\/wp\/v2\/comments?post=22"}],"version-history":[{"count":5,"href":"http:\/\/hdm.brc.riken.jp\/en\/wp-json\/wp\/v2\/pages\/22\/revisions"}],"predecessor-version":[{"id":360,"href":"http:\/\/hdm.brc.riken.jp\/en\/wp-json\/wp\/v2\/pages\/22\/revisions\/360"}],"wp:attachment":[{"href":"http:\/\/hdm.brc.riken.jp\/en\/wp-json\/wp\/v2\/media?parent=22"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}